Platelet Rich Plasma Tennis Elbow Study

Enrollment inwards the almost comprehensive platelet rich plasma written report to engagement was of late completed.  The written report is a double blind randomized lawsuit of 230 patients of PRP vs Saline for chronic lawn tennis elbow.  It followed the protocol outlined inwards the outset published written report on the topic. 
(American Journal of Sports Medicine--Mishra as well as Pavelko, 2006)

It volition conduct maintain 8-10 months to destination the follow upwards as well as analyze the information but it is a milestone to conduct maintain only completed enrollment inwards this of import investigation.  We tin all expect frontwards to the results.

AM
TotalTendon
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Platelet Rich Plasma Forum at AAOS

The American Academy of Orthopaedic Surgery as well as AAOS Now volition travel conducting a Platelet Rich Plasma Forum on Feb 14, 2011 only prior to the Annual Meeting inward San Diego.  Participating inward this coming together are an elite grouping of clinicians as well as researchers including but non express to doc James Andrews, doc Steven Arnoczky, doc Terry Canale, doc William Clancy, doc Freddie Fu, doc Taco Gosens, doc Elizaveta Kon, doc Nicola Maffulli, doc Robert Marx, doc Allan Mishra, doc Pietro Randelli, doc Scott Rodeo, as well as doc JR Woodall.

This grouping along alongside several others has been tasked alongside evaluating the Blue Planet of platelet rich plasma.  It volition travel the close comprehensive tidings of the topic alongside see to orthopedics as well as sports medicine.  The destination is to hopefully brand only about feel of how to best evaluate as well as potentially role PRP.

Stay tuned for details.

AM
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AAOS Now PRP Forum

AAOS Now reported on the recent platelet rich plasma forum inward San Diego.


"The participants of the 2011 PRP Forum too endorsed the evolution of standards inward the industry of PRP, noted that PRP may hold out contraindicated inward to a greater extent than or less conditions, in addition to called for the institution of a study grouping to follow upwardly on the other recommendations resulting from the session."
  
"At the destination of the day, an informal survey of participants found virtually inward understanding that PRP would hold out an option, especially if conservative treatments accept failed in addition to the side past times side pace would hold out surgery."


The grouping agreed that PRP needs a classification system.  Dr. Allan Mishra proposed i that is nether consideration.


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Level One Two Year Follow Up Paper Supports Use of Platelet Rich Plasma for Tennis Elbow

Dr. Taco Gosens in addition to his squad from the Netherlands convey simply published inwards the American Journal of Sports Medicine the best newspaper to appointment on the operate of platelet rich plasma for lawn tennis elbow.  Using the Biomet GPS device to practice platelet rich plasma (Type 1A PRP inwards Mishra's classification organization of PRP), they constitute PRP patients were successfully treated to a greater extent than ofttimes than patients treated amongst corticosteroid injections at ii twelvemonth follow up.  This was highly statistically pregnant at a p value of < 0.0001. 
Read the entire abstract here.

This newspaper confirms that a specific type of PRP is amend than the ofttimes used cortisone injection for chronic lateral epicondylar tendinopathy.  This squad of researchers besides needs to endure congratulated on finishing this of import work. 

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Total Tendon
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Regenerative Medicine Treatment Value Equation

Regenerative medicine is a buzz phrase correct now.  Patients, providers in addition to politicians are all inward favor of "Regenerative Medicine".  There are 3 major components to evaluate when assessing handling value (TV).  Treatment value is straight related to overall efficacy (E) of the drug or physical care for in addition to inversely related to toll (C) in addition to guide chances (R).  A uncomplicated equation tin define it:

TV = east / C x R2

That is Treatment Value = Efficacy divided past times Cost times Risk squared.

We take away treatments of high value amongst maximal efficacy that accept reasonable costs in addition to minimal risks.  When evaluating novel potential "Regenerative Medicine Treatments", catch this equation.

Please post service whatsoever comments or suggestions.

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ApexPRP.com
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New Study shows PRP improves Rotator Cuff Repair Outcomes

Dr. Pietro Randelli together with his colleagues but published a prospective randomized trial on the role of platelet rich plasma for rotator cuff repair surgery.  He showed a specific type of PRP (Increased platelets inwards combination amongst white blood cells) improved outcomes particularly inside the kickoff thirty days.

Platelet rich plasma inwards arthroscopic rotator cuff repair: a prospective RCT study, 2-year follow-up. Authored By: Randelli Pietro; Arrigoni Paolo; Ragone Vincenza; Aliprandi Alberto; Cabitza Paolo Department of Scienze Medico Chirurgiche, University of Milano, IRCCS Policlinico San Donato, Milano, Italy. Pub Date: 06/2011 Source/Vol: Journal of shoulder together with elbow surgical physical care for / American Shoulder together with Elbow Surgeons ... [et al.]/20

Hypothesis  Local application of autologous platelet rich plasma (PRP) improves tendon healing inwards patients undergoing arthroscopic rotator cuff repair. Study Design  Prospective, randomized, controlled, double blind study; considering an alpha flat of 5%, a ability of 80%, 22 patients for grouping are needed. Materials And Methods  Fifty-three patients who underwent shoulder arthroscopy for the repair of a consummate rotator cuff tear were randomly divided into ii groups, using a block randomization procedure. H5N1 handling grouping (N = 26) consisted of those who received an intraoperative application of PRP inwards combination amongst an autologous thrombin component. H5N1 command grouping (N = 27) consisted of those who did non have that treatment. Patients were evaluated amongst validated consequence scores. H5N1 magnetic resonance picture (MRI) was performed inwards all cases at to a greater extent than than 1 twelvemonth post-op. All patients had the same accelerated rehabilitation protocol. Results  The ii groups were homogeneous. The hurting grade inwards the handling grouping was lower than the command grouping at 3, 7, 14, together with thirty days later on surgical physical care for (P < .05). On the Simple Shoulder Test (SST), University of California (UCLA), together with Constant scores, forcefulness inwards external rotation, equally measured past times a dynamometer, were significantly higher inwards the handling grouping than the command grouping at 3 months later on surgical physical care for (strength inwards external rotation [SER]: 3 ± 1.6 vs 2.1 ± 1.3 kg; SST: 8.9 ± 2.2 vs 7.1 ± 2.7; UCLA: 26.9 ± 3 vs 24.2 ± 4.9; Constant: 65 ± ix vs 57.8 ± 11; P < .05). There was no departure betwixt the ii groups later on 6, 12, together with 24 months. The follow-up MRI showed no pregnant departure inwards the healing charge per unit of measurement of the rotator cuff tear. In the subgroup of flat 1 together with ii tears, amongst less retraction, SER inwards the PRP grouping was pregnant higher at 3, 6, 12, together with 24 months postoperative (P < .05). Conclusion  The results of our report showed autologous PRP reduced hurting inwards the kickoff postoperative months. The long-term results of subgroups of flat 1 together with ii tears advise that PRP positively affected cuff rotator healing. Copyright © 2011 Journal of Shoulder together with Elbow Surgery Board of Trustees. Published past times Mosby, Inc. All rights reserved. Publication Types: Journal Article PubMed Link: http://www.ncbi.nlm.nih.gov/pubmed/21570659

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Platelet Rich Plasma Classification Video

This is a Platelet Rich Plasma Classification System proposed by Dr. Allan Mishra at the American Academy of Orthopedic Surgery (AAOS) inwards San Diego Feb. 2011



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Total Tendon.com
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AAOS Now Reports on Platelet Rich Plasma

AAOS NOW simply published a word nearly what's behind the hype of platelet rich plasma  Read an excerpt below:  
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"Dr. Mishra equally good presented a concise classification scheme for PRP formulations (See Video of PRP Classification) to assistance compare information from diverse studies. The scheme takes into concern human relationship the inclusion of white blood cells, the improver of a thrombin activator, together with the terminal concentration of platelets.

He noted that PRP is “autologous engineering” a agency to assistance maximize how the torso helps heal itself. Stem cells together with os marrow are other examples.

“Patients are seeing elite athletes, similar Tiger Woods together with Raphael Nadal, beingness treated alongside to a greater extent than or less shape of PRP together with are shout for their orthopaedic surgeons to give them ‘what Tiger got.’ The occupation is that nosotros don’t know ‘what Tiger got,’ what happened to him earlier or afterwards, or what was used, together with no ane is publishing that data,” noted MD Mishra.

“But all 3 major sports organizations—the National Football League (NFL), Major League Baseball, together with the National Basketball Association—as good equally the World Anti-Doping Agency, induce got declared that PRP is a reasonable treatment, despite the fact that nosotros may all handgrip that there’s express query to back upwards the efficacy of its use,” he continued.


Read the amount article.
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Clearly, PRP needs to a greater extent than evidence to endure fully validated.  This volition require investigation of specific PRP formulations together with specific indications alongside of import but expensive large randomized trials.  Athletes inwards general, however, create non expect until at that spot is definitive proof.  They are constantly searching for the best ways to recover from injuries together with PRP has increasing evidence that it may help.

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TotalTendon.com

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Kobe Bryant, Tiger Woods together with Platelet Rich Plasma

According to published reports, Kobe Bryant has had iii arthroscopic (scopes) surgeries on his correct knee.  (2003, 2006 in addition to 2010)  This is like to the iii surgeries that Tiger Woods has had on his left knee.  Both of these athletes are inwards their 30s in addition to the enquiry for both of them is:  What is going on within these elite human knee joints in addition to why did they both plough to platelet rich plasma to potentially aid them?

BLOODCURE thinks it is prophylactic to assume that both of them convey only about arthritic changes inwards their knees.  This agency that they convey lost only about of both the smoothen cartilage roofing the os (articular cartilage) in addition to only about of the cushioning cartilage betwixt the thigh in addition to shin bones (meniscus cartilage).  In Tiger's case, he may convey been treated for patellar tendonitis afterwards an ACL reconstruction but at that topographic point is no presented or published data well-nigh the specifics of his treatment.  In Kobe's case, he may convey been treated for human knee arthritis but despite BLOODCURE contacting its many sources inwards the USA in addition to Europe, no 1 has come upwards frontward amongst specific data well-nigh his treatment.  What did he convey done in addition to why did he move to Federal Republic of Federal Republic of Germany to acquire it done?  Plenty of physicians within the USA in addition to specifically California convey sense amongst PRP.  So, did he acquire only about shape of PRP that is non available inwards the USA?

Answers to these questions volition aid us all amend empathize the value of PRP for iconic professional person athletes in addition to for sports medicine inwards general.  Importantly, nosotros too require to larn what type of PRP (many exist) they received.  Here is a video of a PRP Classification System.  

If anyone has data well-nigh these cases, delight postal service a comment below.

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Total Tendon.com
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Platelet Rich Plasma Issue of Operative Techniques inwards Sports Medicine

The entire September 2011 number of Operative Techniques inwards Sports Medicine is dedicated to Platelet Rich Plasma. (PRP) Articles included inwards this number beak over what is platelet rich plasma, how it is before long beingness used inwards the elbow, shoulder, together with foot/ankle.  Discussions most the basic scientific discipline of PRP, its effects on cartilage together with fifty-fifty the coding together with reimbursement of PRP are outlined.  Finally, a newspaper on the futurity of PRP together with its acquit upon on sports medicine is presented.

Elite PRP researchers including exactly non express to:  Lisa Fortier, Brian Cole (Editors), Scott Rodeo, Steven Arnoczky, James Bradley, Augustus D. Mazzocca, Anthony A. Romeo, Allan Mishra, Taco Gosens, Lew Schon, Tomasz Bielecki, together with David M. Dohan Ehrenfest are amid the authors.

This represents the latest data most PRP from the people who convey been actively engaged inwards evaluating it scientifically. 

To review the entire number click here:  Operative Techniques inwards Sports Medicine PRP Issue

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Total Tendon
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Risk together with Innovation

Novel transformative solutions require risk. We postulate to increase the incentives to cause got such risk.  Using platelet rich plasma for sports related injuries a decade agone was crazy.  Now it is commonplace in addition to backed upward alongside degree i information for chronic problems such equally lawn tennis elbow.  


How tin rank the sack nosotros encourage providers in addition to payers to cause got to a greater extent than risks to assistance patients?


AM
Total Tendon
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Steve Jobs World's Top Innovator

Who volition supervene upon Steve Jobs equally the world's occur innovator? Searching for "productive narcissists."  Another question:  Is it possible to endure cracking in addition to too good?
 WSJ Reports.http://online.wsj.com/article/SB10001424052970203476804576617432977807982.html
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Elite Athletes instruct out along to Embrace Platelet Rich Plasma

Ryan Howard (Phillies commencement baseman) has Achilles Tendon Repaired as well as and thus augmented amongst Platelet Rich Plasma.  It is clear that elite athletes are all the same embracing PRP.  

http://www.foxnews.com/sports/2011/10/12/phillies-1b-howard-has-surgery/

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Total Tendon
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Platelet Rich Plasma as well as Stem Cell Treatments inward Athletes

Platelet Rich Plasma (PRP) in addition to Stem Cell Therapies are becoming to a greater extent than unremarkably used peculiarly yesteryear elite athletes.  In social club to ameliorate empathize the orbit of the situation, I accept pose upwards an interactive site alongside links to whatever in addition to all articles near either PRP or Stem Cell Treatments inwards Athletes.   Reasons why elite athletes are seeking out stalk jail mobile telephone in addition to platelet rich plasma therapies:

• They desire to instruct ameliorate in addition to instruct dorsum to their sport at the highest grade equally fast equally possible.
• They are dissatisfied alongside acquaint treatments or those treatments are non working.  
• They empathize that using the regenerative components of your ain blood, os centre or fatty to process injured or degenerative tissue makes intrinsic sense.
• They are farther willing to live on treated alongside these autologous biologic products despite the immaturity of the supporting data.

Please view the site in addition to add together to the listing of athletes in addition to articles.  This is business office of a projection to ameliorate empathize how in addition to why athletes are seeking out these types of treatments in addition to how effective they are. Please role a brusk ane business description alongside links.  Part of the listing is outlined below:  

• Tiger Woods (Golf) PRP
• Hines Ward (Football) PRP
• Peyton Manning (Football) Stem Cells
• Kobe Bryant (Basketball) PRP Stem Cells
• Terrell Owens (Football) Stem Cell
• Cliff Lee (Baseball) PRP

Updates tin live on institute via twitter: @bloodcure in addition to via this .com blog


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Total Tendon
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Some thoughts on the Future of Medicine

Genome information interpretation volition emerge equally its ain medical specialty much similar radiology for evaluation of xrays, CTs & MRIs.  It volition stimulate got roughly fourth dimension only the complexity of the information volition eventually Pb to a board certified specialist that helps main attention doctors empathize genetic tests.  

Transformative solutions to a greater extent than oft arise via iconoclastic horizons non via the cognoscenti.  Translation:  Truly pregnant advances produce non arise from established ideas in addition to people.   They destroy established ideas in addition to patterns of behavior.  


"Citizen Scientists" in addition to "Health Hackers" Conducting trials, analyzing information in addition to presenting papers.   How tin nosotros all assistance inwards the advancement of science:  
http://online.wsj.com/article/SB10001424052970204621904577014330551132036.html

Tumor Treating Fields (electrical current) used to process encephalon cancer. 1st prescription patient. Novel GBM treatment

http://medicalxpress.com/news/2011-12-patient-prescription-fda-approved-brain-tumor.html

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Medicare Database

Medicare to allow role of its database to charge per unit of measurement Doctors, Hospitals in addition to other Health Care Providers.  This volition atomic number 82 to mobile apps to figure out what doctors in addition to hospitals perform the virtually operations in addition to what their success in addition to failure rates are past times procedure.  It volition likewise accept unintended consequences.  


http://news.yahoo.com/feds-allow-medicare-data-rate-doctors-175246424.html
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Chicago Bear is treated amongst Platelet Rich Plasma

Chicago Bear Matt Forte has platelet rich injection for knee articulation ligament injury.  

http://espn.go.com/blog/nfcnorth/post/_/id/35552/have-at-it-matt-fortes-best-strategy
To acquire to a greater extent than almost PRP, visit:  http://www.apexprp.com

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Kobe Bryant Platelet Rich Plasma

Kobe Bryant returns to play amongst LA Lakers afterwards beingness treated amongst platelet rich plasma derivative. See video. 



More PRP information
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ABC Evening News Platelet Rich Plasma

ABC broadcasts storey most how platelet rich plasma is beingness used to process lawn tennis elbow this night on the even out news.  Randomized, controlled trials directly back upwardly the piece of job of platelet rich plasma for chronic lawn tennis elbow when compared to the measure help of a cortisone shot.  Someday PRP may completely supercede cortisone.  For to a greater extent than PRP information, visit:  ApexPRP.com

To stance the ABC Story:  

http://abcnews.go.com/Health/Wellness/cutting-edge-joint-injections-heal-baby-boomer-arthritis/story?id=15214643#.TvP_PSNWqiV

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AAOS Platelet Rich Plasma Symposium

The American Academy of Orthopaedic Surgeons (AAOS) volition last asset its annual coming together this calendar week inward San Francisco.  The AAOS is sponsoring a symposium on Platelet Rich Plasma on Wed Feb. eighth at 10.30 am PST.  This volition characteristic talks nearly the exercise of PRP inward the purpose or operating room for achilles tendonitis, rotator cuff tears, lawn tennis elbow, ligament injuries, too articulatio genus osteoarthritis amidst others.  Leading experts volition struggle its value.

I volition last sending out alive updates via my twitter account:  @

Follow if y'all would similar to sentiment them inward existent time.  

This symposium volition acquaint simply about of the latest question on the topic of PRP for musculoskeletal injuries too disorders.

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Total Tendon

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