Regenerative Medicine Treatment Value Equation

Regenerative medicine is a buzz phrase correct now.  Patients, providers in addition to politicians are all inward favor of "Regenerative Medicine".  There are 3 major components to evaluate when assessing handling value (TV).  Treatment value is straight related to overall efficacy (E) of the drug or physical care for in addition to inversely related to toll (C) in addition to guide chances (R).  A uncomplicated equation tin define it:

TV = east / C x R2

That is Treatment Value = Efficacy divided past times Cost times Risk squared.

We take away treatments of high value amongst maximal efficacy that accept reasonable costs in addition to minimal risks.  When evaluating novel potential "Regenerative Medicine Treatments", catch this equation.

Please post service whatsoever comments or suggestions.

AM
ApexPRP.com
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Kobe Bryant, Tiger Woods together with Platelet Rich Plasma

According to published reports, Kobe Bryant has had iii arthroscopic (scopes) surgeries on his correct knee.  (2003, 2006 in addition to 2010)  This is like to the iii surgeries that Tiger Woods has had on his left knee.  Both of these athletes are inwards their 30s in addition to the enquiry for both of them is:  What is going on within these elite human knee joints in addition to why did they both plough to platelet rich plasma to potentially aid them?

BLOODCURE thinks it is prophylactic to assume that both of them convey only about arthritic changes inwards their knees.  This agency that they convey lost only about of both the smoothen cartilage roofing the os (articular cartilage) in addition to only about of the cushioning cartilage betwixt the thigh in addition to shin bones (meniscus cartilage).  In Tiger's case, he may convey been treated for patellar tendonitis afterwards an ACL reconstruction but at that topographic point is no presented or published data well-nigh the specifics of his treatment.  In Kobe's case, he may convey been treated for human knee arthritis but despite BLOODCURE contacting its many sources inwards the USA in addition to Europe, no 1 has come upwards frontward amongst specific data well-nigh his treatment.  What did he convey done in addition to why did he move to Federal Republic of Federal Republic of Germany to acquire it done?  Plenty of physicians within the USA in addition to specifically California convey sense amongst PRP.  So, did he acquire only about shape of PRP that is non available inwards the USA?

Answers to these questions volition aid us all amend empathize the value of PRP for iconic professional person athletes in addition to for sports medicine inwards general.  Importantly, nosotros too require to larn what type of PRP (many exist) they received.  Here is a video of a PRP Classification System.  

If anyone has data well-nigh these cases, delight postal service a comment below.

AM
Total Tendon.com
Sumber http://plateletrichplasma.blogspot.com

Platelet Rich Plasma Issue of Operative Techniques inwards Sports Medicine

The entire September 2011 number of Operative Techniques inwards Sports Medicine is dedicated to Platelet Rich Plasma. (PRP) Articles included inwards this number beak over what is platelet rich plasma, how it is before long beingness used inwards the elbow, shoulder, together with foot/ankle.  Discussions most the basic scientific discipline of PRP, its effects on cartilage together with fifty-fifty the coding together with reimbursement of PRP are outlined.  Finally, a newspaper on the futurity of PRP together with its acquit upon on sports medicine is presented.

Elite PRP researchers including exactly non express to:  Lisa Fortier, Brian Cole (Editors), Scott Rodeo, Steven Arnoczky, James Bradley, Augustus D. Mazzocca, Anthony A. Romeo, Allan Mishra, Taco Gosens, Lew Schon, Tomasz Bielecki, together with David M. Dohan Ehrenfest are amid the authors.

This represents the latest data most PRP from the people who convey been actively engaged inwards evaluating it scientifically. 

To review the entire number click here:  Operative Techniques inwards Sports Medicine PRP Issue

AM
Total Tendon
Sumber http://plateletrichplasma.blogspot.com

7 Billion People on footing Very Soon

7 Billion people on public soon. We require to a greater extent than efficient ways of discovering together with developing transformative therapies.

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Some thoughts on the Future of Medicine

Genome information interpretation volition emerge equally its ain medical specialty much similar radiology for evaluation of xrays, CTs & MRIs.  It volition stimulate got roughly fourth dimension only the complexity of the information volition eventually Pb to a board certified specialist that helps main attention doctors empathize genetic tests.  

Transformative solutions to a greater extent than oft arise via iconoclastic horizons non via the cognoscenti.  Translation:  Truly pregnant advances produce non arise from established ideas in addition to people.   They destroy established ideas in addition to patterns of behavior.  


"Citizen Scientists" in addition to "Health Hackers" Conducting trials, analyzing information in addition to presenting papers.   How tin nosotros all assistance inwards the advancement of science:  
http://online.wsj.com/article/SB10001424052970204621904577014330551132036.html

Tumor Treating Fields (electrical current) used to process encephalon cancer. 1st prescription patient. Novel GBM treatment

http://medicalxpress.com/news/2011-12-patient-prescription-fda-approved-brain-tumor.html

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Medicare Database

Medicare to allow role of its database to charge per unit of measurement Doctors, Hospitals in addition to other Health Care Providers.  This volition atomic number 82 to mobile apps to figure out what doctors in addition to hospitals perform the virtually operations in addition to what their success in addition to failure rates are past times procedure.  It volition likewise accept unintended consequences.  


http://news.yahoo.com/feds-allow-medicare-data-rate-doctors-175246424.html
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Kobe Bryant Platelet Rich Plasma

Kobe Bryant returns to play amongst LA Lakers afterwards beingness treated amongst platelet rich plasma derivative. See video. 



More PRP information
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ABC Evening News Platelet Rich Plasma

ABC broadcasts storey most how platelet rich plasma is beingness used to process lawn tennis elbow this night on the even out news.  Randomized, controlled trials directly back upwardly the piece of job of platelet rich plasma for chronic lawn tennis elbow when compared to the measure help of a cortisone shot.  Someday PRP may completely supercede cortisone.  For to a greater extent than PRP information, visit:  ApexPRP.com

To stance the ABC Story:  

http://abcnews.go.com/Health/Wellness/cutting-edge-joint-injections-heal-baby-boomer-arthritis/story?id=15214643#.TvP_PSNWqiV

AM
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Platelet Rich Plasma vs Hyaluronate for Ankle Pain in addition to Disability

Am J Sports Med. 2012 January 17. 

Platelet-Rich Plasma or Hyaluronate inwards the Management of Osteochondral Lesions of the Talus.

Mei-Dan O, Carmont MR, Laver L, Mann G, Maffulli N, Nyska M.

Source

Department of Orthopedic Surgery, Meir University Hospital, Kfar-Saba, Israel.

Abstract

BACKGROUND:

Nonoperative options for osteochondral lesions (OCLs) of the talar dome are limited, as well as currently, at that topographic point is a lack of scientific evidence to lead management.

PURPOSE:

To evaluate the short-term efficacy as well as security of platelet-rich plasma (PRP) compared amongst hyaluronic acid (HA) inwards reducing hurting as well as disability caused past times OCLs of the ankle.

STUDY DESIGN:

Randomized controlled trial; Level of evidence, 2.

METHODS:

Thirty-two patients aged xviii to threescore years were allocated to a handling past times intra-articular injections of either HA (group 1) or PRP (plasmarich in growth factors [PRGF] technique, grouping 2) for OCLs of the talus. Thirty OCLs, xv per arm, received 3 consecutive intra-articular therapeutic injections as well as were followed for 28 weeks. The efficacy of the injections inwards reducing hurting as well as improving business office was assessed at each take in using the American Orthopaedic Foot as well as Ankle Society (AOFAS) Ankle-Hindfoot Scale (AHFS); a visual analog scale (VAS) for pain, stiffness, as well as function; as well as the subjective global business office score.

RESULTS:

The bulk of patients were men (n = 23; 79%). The AHFS grade improved from 66 as well as 68 to 78 as well as 92 inwards groups i as well as 2, respectively, from baseline to calendar week 28 (P < .0001), favoring PRP (P < .05). Mean VAS scores (1 = asymptomatic, 10 = severe symptoms) decreased for hurting (group 1: 5.6 to 3.1; grouping 2: 4.1 to 0.9), stiffness (group 1: 5.1 to 2.9; grouping 2: 5.0 to 0.8), as well as business office (group 1: 5.8 to 3.5; grouping 2: 4.7 to 0.8) from baseline to calendar week 28 (P < .0001), favoring PRP (P < .05 for stiffness, P < .01 for function, P > .05 for pain). Subjective global business office scores, reported on a scale from 0 to 100 (with 100 representing healthy, preinjury function) improved from 56 as well as 58 at baseline to 73 as well as 91 past times calendar week 28 for groups i as well as 2, respectively (P < .01 inwards favor of PRP).

CONCLUSION:

Osteochondral lesions of the talocrural articulation treated amongst intra-articular injections of PRP as well as HA resulted inwards a decrease inwards hurting scores as well as an growth inwards business office for at to the lowest degree half-dozen months, amongst minimal adverse events. Platelet-rich plasma treatment led to a significantly improve lawsuit than HA.

Interesting novel data.

AM

Total Tendon

ApexPRP.com

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