Friday, November 3, 2017

DNA Structure Discovered sixty Years Ago


One of the world's nearly of import scientific papers was published inwards the magazine Nature on Apr 25, 1953, lx years agone today.  The entire newspaper was only 1 page!  In the curt communication, James Watson together with Francis Crick non alone detailed the definitive construction of DNA (deoxyribonucleic acid)  but too proposed the unzipping machinery past times which the molecule could replicate itself.  They initially announced they had constitute "the cloak-and-dagger of life" at the Eagle Pub in Cambridge, England.    (See the deoxyribonucleic acid diagram from the actual newspaper to the right)

These 2 vivid men figured out the chemic construction of deoxyribonucleic acid without doing whatever experiments.  They started past times carefully digested together with and thus synthesizing the world's literature.  They attended conferences together with sought information anywhere they could notice it.  They were ridiculed for edifice stick models instead of conducting costly together with fourth dimension consuming lab investigations.  The solution to the beautiful double helix construction of deoxyribonucleic acid arose via the collaboration of biologist Watson together with physicist Crick.  Neither 1 of them had an elite agreement of chemistry.  They fifty-fifty challenged together with eventually proved incorrect the triple helix construction proposed past times famous pharmacist Linus Pauling.  

Sixty years later, their uncovering together with the subsequent interrogation on recombinant deoxyribonucleic acid together with genomic sequencing has transformed our lives.  Today, nosotros conduct maintain for granted our mightiness to "grow" human insulin inwards bioreactors together with target specific cancers amongst molecular designer drugs.  It is appropriate to intermission for only a 2d today together with give cheers the 2 dreamers who via their difficult move together with intuition discovered the construction of DNA.  Let's promise nosotros tin notice together with encourage many to a greater extent than dreamers similar Watson together with Crick.


References:  Watson together with Crick,  Nature Apr 1953

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