Can Stem Cells Cure Knee Arthritis?

Can Stem Cells Cure Knee Arthritis?

Unfortunately, the response to that query is non known today.  It is clear, however, that many new regenerative therapies are emerging to assist the tens of millions of patients worldwide that are suffering from knee articulation arthritis.

First, nosotros must explore what type of stalk cells could last helpful inwards the handling of arthritis.  Stem cells of diverse types tin last obtained from your blood (peripheral derived stalk cells), os marrow (mesenchymal stalk cells), fatty (adipose derived stalk cells), together with fifty-fifty from umbilical cord blood.  Studies today are exploring diverse ways to extract, purify together with concentrate many types of stalk cells.  The cells tin together with thus last injected equally a time out into your knee, used equally business office of surgical physical care for or fifty-fifty injected afterwards an operation.

Microfracture of Damaged Knee Cartilage

One recent written report (Vangsness et al 2014) showed how an injection of mesenchymal stalk cells could Pb to to a greater extent than meniscus tissue afterwards a knee articulation arthroscopy.  24% of the treated grouping were establish to cause got at to the lowest degree 15% increased meniscal volume.  This is a pocket-size sum inwards solely a a quarter of the patients but it does correspond a start.  Another written report published final twelvemonth (Saw et al 2013), injected peripheral derived stalk cells afterwards a microfracture physical care for together with noted improvement inwards the cartilage quality.  Other approaches (Pak et al 2014) purpose adipose derived stalk cells from liposuction inwards combination amongst platelet-rich plasma to care for meniscus tears.  Finally, a review (Anderson et al 2013) of potential stalk jail cellular telephone therapies for knee articulation cartilage outlines many potential together with emerging options.

Also, a multifariousness of procedures equally good purpose non-stem cells to care for arthritis of the knee.  One of the oldest is called autologous chondrocyte implantation.  This is where a biopsy of your ain cartilage is taken together with and thus grown inwards a lab.  The expanded cells together with and thus reimplanted into an arthritic lesion of the knee.  Another physical care for merely penetrates the os nether the defective cartilage.  This leads to leakage of to a greater extent than or less of the os marrow along amongst your ain the stalk cells inside the marrow into the defect.  This is called microfracture.  Yet to a greater extent than or less other physical care for uses juvenile cartilage that is minced together with and thus glued into a arthritic zone of the knee.

It is clear that at that topographic point are many competing approaches to the purpose of cells together with stalk cells to care for knee articulation arthritis.  None cause got "cured" the problem.   There is, however, an earnest worldwide enquiry essay that volition attain clinically meaningful options for clinicians together with patients.

Millions worldwide are waiting for that day.

AM
TotalTendon

References
Anderson et al 2013
Saw et al 2013
Vangsness et al 2014
Pak et al 2014

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