Friday, November 3, 2017

Monitoring Brain Tumors without Surgery

Glioblastoma is i of thethe most mutual in addition to most lethal forms of encephalon cancer.  Monitoring the potential for it to spread or invade is a critical element of treatment.  Influenza A virus subtype H5N1 new method of sampling spinal fluid for genetic markers called microRNAs has late been developed that holds meaning promise.  This is an first-class example of how medicine is inward the procedure of beingness radically transformed past times genetic tests. 

See press unloosen below.

AM


Researchers uncovering non-surgical examination for encephalon cancer



Test volition allow for patients amongst encephalon tumors to live diagnosed in addition to monitored without the ask for surgery


Boston – In a breakthrough for the fashion encephalon cancer is diagnosed in addition to monitored, a squad of researchers, atomic number 82 past times Anna M. Krichevsky, PhD, of the Center of Neurologic Diseases at Brigham in addition to Women's Hospital (BWH) inward Boston in addition to Santosh Kesari, MD, PhD, manager of Neuro-Oncology at UC San Diego Moores Cancer Center, accept demonstrated that encephalon tumors tin live reliably diagnosed in addition to monitored without surgery. Previously, an accurate non-surgical examination to uncovering encephalon tumors was unavailable in addition to methods of monitoring a encephalon tumor's progression or answer to handling were non reliable. The results from this airplane pilot report are published inward the online edition of Neuro-Oncology.


"We are excited nigh the potential that this examination has to repose the procedure of detecting in addition to monitoring encephalon tumors," said Krichevsky. "The examination needs to live farther developed earlier it is used inward a clinical setting, but I facial expression it could live peculiarly valuable for patients who are non surgical candidates due to the tumor's size or location, or due to an underlying medical condition."


In a report of 118 patients amongst dissimilar types of encephalon cancers, researchers showed that microRNA profiling of cerebrospinal fluid tin live used to arrive at upward one's hear the presence of glioblastoma, the most mutual in addition to lethal type of encephalon tumor. The examination utilizes microRNAs, tiny RNA molecules that supply first-class biomarkers for diverse conditions, in addition to whose levels tin live accurately measured inward trunk fluids only in addition to inexpensively. The same procedure tin live used to uncovering the presence of cancer that started inward roughly other purpose of the trunk in addition to spread to the brain, in addition to furthermore, the procedure tin likewise live used to monitor the tumor every bit it is treated.


A patent related to the examination is pending. The report was funded past times National Institutes of Health grants [R01CA138734-01A1, K08CA124804, in addition to ARRA 3P30CA023100-25S8, the Sontag Foundation in addition to the James S. McDonnell Foundation.

Link to amount press release.


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